The purpose of this study was to compare the several combinatorial cariostatic potentials of experimental dentifrices containing an herbal extract, catechin, in combination of sodium fluoride and/or triclosan in silica base. The chemical and microbial cyclic remineralization procedures were used to measure the effect of each dentifrices. Subsurface caries lesions were prepared by exposing extracted, flattened and polished bovine enamel cores to lactate-Carbopol system for 48 hours. The delta VHNs were determined and analyzed by one-way ANOVA and Newman-Keul procedures for the multiple Student´s t-test as described previously.
The results of each test dentifrices are summarized as followings;
Effects of the different dentifrices on surface hardness according to pH cycling methods (delta VHN±S.D.)
Test Dentifrice (Silica Base) Chemical model Microbial model
Negative Control (No Active Agent) 8.3± 3.9 7.0± 6.0
Paste A (0.4% catechin) 11.8± 3.9 11.4± 5.0
Paste B (NaF & tridosan) 18.9± 5.6 28.2± 8.4
Positive Control (NO) 22.9± 5.3 22.0± 5.6
Paste C (NaF, tridosan & 0.4% catechin) 26.2± 10.0 43.6± 10.6
Colgate Total* (NaF & tridosan) 34.4± 8.7 51.4± 9.2
These results showed that (1) the addition of herbal component, catechin numerically increased surface hardness in both test models, (2) the fluoride dentifrices significantly increased surface hardness (p <0.05) as compared to the negative control, and (3) the specimens tested in the microbial cyclic model showed a highly significant cariostatic benefit of Paste C and Colgate Totaldentifrices (p (0.001) as compared to the other test dentifrices.
All the presented findings support the conclusion that catechin is enough to cariostatic effect if adden in toothpaste.
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